Skip to product information

VSL#3® Capsules

VSL#3® Capsules

 (3852 Reviews)
Regular price $59.36
Regular price $59.36 Sale price $65.95
SAVE 9% Sold out

VSL#3®  Probiotics for Digestive Health, IBS &UC Symptoms - 112.5B CFUs, High-Potency,Multi-Strain, Live, Refrigerated Probiotic,Medical Food for Gut Health Support in Men &Women, 60 Capsules

BUNDLE & SAVE

VSL#3® Capsules

VSL#3® Capsules

Regular price $59.36
Regular price $59.36 Sale price $65.95
SAVE 9% Sold out
check_box

Free From Common Irritants:

  • Dairy-Free
  • Gluten-Free
  • Soy-Free
  • Nut-Free
  • No GMOs
  • Vegan
View full details

    INGREDIENTS

    • Probiotic strains: Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. longum), Bifidobacterium lactis (previously classified as B. infantis), Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus helveticus (previously classified as L. delbrueckii subsp. bulgaricus)
    • Other ingredients: ­Vegetal capsule (hydroxypropyl methylcellulose), cornstarch, magnesium stearate, silicon dioxide, stearic acid, microcrystalline cellulose­.

    Product Core Benefits

    check_circle
    Clinically supported:

    Backed by scientific research and trusted by healthcare professionals.

    check_circle
    Ultra-high-potency, multi-strain blend:

    112.5 billion CFU per capsule from 8 complementary probiotic strains to help maintain a balanced intestinal microbiota.

    check_circle
    Refrigerated to preserve potency:

    Stored and shipped cold to ensure live cultures stay potent throughout shelf life.

    check_circle
    Precisely manufactured:

    Produced under GMP-certified conditions, free from dairy, gluten, and other common irritants.

    Recommended Dosage

    Typical adult dosage is 1–2 capsules up to 4 times daily, or as directed by a physician.

    Administration & Notes

    Swallow whole or mix into a non-carbonated cold beverage or food. Avoid consuming with hot foods or drinks, as heat may reduce probiotic viability.

    Suggested Usage Cycle

    Consistent use for several weeks may be needed to support microbiota balance.

    Detailed Instructions Reference

    For more information on how to take VSL#3® for the dietary management of certain GI conditions, please see the VSL#3® Product Information Sheet.

    Important Product Notice

    VSL#3® is a medical food intended to be used under medical supervision.

    HOW TO USE

    • Probiotic Pioneer, Gut Health Leader.

      VSL#3® is an ultra-high-potency probiotic medical food — and the #1 gastroenterologist-recommended multi-strain probiotics brand.
      Developed for people with serious gastrointestinal conditions, it’s trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.

    • Built on Science.Proven in Practice.


      Driven by research — not marketing trends —
      VSL#3® is trusted in clinical care for the dietary
      management of specific gastrointestinal
      conditions. It continues to set the standard for
      potency, consistency, and reliability in probiotic
      therapy.

    • Ultra-High-Potency.Guaranteed.


      VSL#3® products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3® guarantees potency through expiration when stored as directed.

    • Ultra-High-Potency.Guaranteed.


      VSL#3® products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3® guarantees potency through expiration when stored as directed.

      Science Over Hype.

       

      Designed for Viability

      Probiotics need to survive storage & digestion to work. VSL® uses premium strains, stable formula and professional packaging to guarantee viable bacteria till expiry.

      VSL#3® is maintained under strict cold-chain conditions — refrigerated throughout production, storage, and shipping — to help preserve live strains at their intended strength.

      Science-Led Strain Selection

      Our formulas are science-based. We pick verified strains proven to balance gut microbiome, backed by long-term probiotic research.
      All VSL products follow scientific standards from strain selection to finished goods, delivering steady quality across the whole product line.

      A Legacy of Expertise

      VSL® Probiotics builds on the legacy of VSL#3® — a formulation long trusted by healthcare professionals for its quality and reliability. That foundation continues to guide how we develop every product in the VSL® Probiotics family.Our focus is clear: to create formulations grounded in evidence, crafted with precision, and respected for their consistency — not driven by trends, but by trust earned through experience.

      Our Purpose: Science That Serves People

      Gut microbiome health varies from person to person.
      VSL® Probiotics connects microbiome research with daily wellness, creating targeted probiotic formulas to ease digestive issues and maintain intestinal & vaginal health.

      Our flagship VSL#3® is a globally recognized medical-grade probiotic trusted by medical experts. Alongside series products for gut and vaginal care, we stick to high potency and strict quality standards, backed by clinical studies to advance microbiome science for professional medical use and daily health care.

      The VSL® Difference: Proven. Precise. Trusted.

      VSL® Probiotics builds on the legacy of VSL#3® — a formulation trusted by healthcare professionals for its quality, consistency, and reliability. That same foundation guides every product in the VSL® Probiotics family, from clinically studied medical foods to precision-formulated daily supplements.Our focus remains the same: creating probiotic formulations grounded in evidence, crafted with precision, and respected for their consistency — not driven by trends, but by trust earned through experience.

      FAQs about VSL#3®

      Collapsible row

      What is VSL#3®?

      VSL#3® is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).

      How should I store VSL#3®?

      VSL#3® should be stored under refrigeration at 36–46°F (2–8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.

      What is a Medical Food?

      Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.

      How to use VSL Capsule?

      Take this medicine in the dose and duration as advised by your doctor.VSL#3® Capsule may be taken with or without food

      How does VSL#3® compare to a Low FODMAP diet for IBS management?

      In a 2021 clinical study, VSL#3® demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet¹ — a commonly recommended but restrictive approach. Because VSL#3® is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.

      ¹Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.

      How are VSL#3® and VSL4® Gut different?

      Although both products contain the same 8 probiotic strains, they are formulated and labeled for different purposes. VSL#3® is a refrigerated, ultra-high-potency probiotic medical food for the dietary management of specific GI conditions. VSL4® Gut is a probiotic supplement designed to support digestive comfort, regularity, and overall gut health.

      • Works Great!

        Really calms my Gut. I'm so thankful mydoctor recommended this product! It workswell everyday.

        Carol F.

      • Proven product

        This probiotic has worked wonders with issues of UC. I can really tell a difference when I forget a dose.

        Debra M.

      • Wonderful Probbiotic

        This is the only probiotic that works for me!

        Daryl R

      • Love those VSL3.COM Capsules

        Very happy to be taken the VSL Capsules. Have been on them going on three yrs and they take care of my problem.

        Carol S.

      • Very happy with results!

        Great stuff! Really helps with stomach issues!!

        RoseAnn R.

      • Tryit!

        This isn't optional if you have IBS. It's a must have! It helps with cramping. bloating, and gas. I can't go without it!

        Marissa

      • The best

        Is the best probiotic I have taken. I have been taking VSL for 2 years it stopped my stomach problem..

        donna n.

      • Great for gut issues

        They are very effectve to kep you regularand healthy. Iwanted to take them daly but they are too poverful sol take them every two days now. Highly recomnended for aryone who has

        Tony Y.

      • VSL#3 works for me!

        It works as expected. I can see the difference and the improvement

        Rafik B.